Hormone Replacement Therapy

The basics of women's hormone replacement therapy

BHRT improves quality of life dramatically

Natural Hormone Replacement Therapy or Bio-Identical Hormone Replacement Therapy (BHRT) is used to help treat the symptoms of menopause, perimenopause and post-menopause.


Menopause symptoms are related to a deficiency of estrogen and progesterone.  The vasomotor symptoms of menopause include hot flashes and night sweats.  The genito-urinary symptoms of menopause include vaginal dryness, pain with intercourse and urinary problems.  Symptoms in other systems include dry skin, sagging breasts, osteoporosis, cardiovascular disease, cognitive impairment and Alzheimer's dementia.  


Treatment with natural hormones usually includes creating a unique combination of hormones for the individual patient, based on their hormone deficiencies. These are often referred to as "custom-compounded"  hormone products. The major benefit of this type of treatment is that doses are individualized, and the mixture of products may not be commercially available.  Blood tests are required to confirm appropriate dosing.

bio-identical vs natural hormones

image25

Bio-Identical vs natural hormones

Non-bio-identical synthetic progesterone analogues (called progestins) are often confused  with the natural hormone progesterone.  Progestins have been shown to increase the risk of breast cancer while progesterone has been shown to decrease the risk of breast cancer.  Estrogens are also different: horse  estrogen is the most commonly prescribed, but have been shown to cause  heart attacks, stokes, and blood clots, where as Bio-Identical estrogen does not. The Women's Health Initiative Study did not use real estrogen or progesterone.  Because of these safety concerns, Dr. Borgardt feels strongly that only 

Bio-Identical hormones should be used in hormone  replacement.  


Because  these hormones are natural, they are not patentable.  Studies have  indicated that these hormones are safer than, and as effective as, non-identical (patentable) synthetic or animal hormones. The FDA has permitted the marketing of approved natural hormones in standardized formulations.  


image26

Premarin and Provera are dangerous and should not be used for hormone replacement therapy.

The  Women's Health Initiative Randomized Controlled Trial which was published in the July 17, 2002 issue of The Journal of American Medical Association Vol 288 No. 3, showing that PremPro, the combination of Premarin (non-human estrogens derived from pregnant mare-horse urine) and Provera (Medroxyprogesterone acetate) was dangerous. This type of "hormone replacement therapy" is not really true hormone replacement therapy since to be categorized as "hormone" the substance must naturally exist in the human female or male body. The results of the PremPro study do not apply to Bio-Identical hormone replacement.

image27

Bio-Identical hormone replacement is essential to maintain female quality of life.

Large scale studies of bio-identical hormones compared with artificial hormones were presented at the American College of Physicians in 2013.  Studies showed that topical estradiol decreases your risk of breast cancer, and does not cause heart attacks and strokes.  Bio-Identical progesterone does not increase the risk of breast cancer like artificial progesterone. Let's stick with Bio-Identical hormone replacement therapy.